Department of Veterinary Clinical Pathology, Faculty of Veterinary Medicine, University of Cordoba, Spain.
Gomez-Villamandos R.J., Santisteban-Valenzuela J.M., Ruiz-Calatrava I., Gomez-Villamandos J.C., Avila-Jurado I.
A study was made of the effects of low level laser irradiation on the cicatrisation on superficial wounds in the pharyngeal mucosa of the horse. Duplicate pharyngeal mucosal ulcers were included in 12 spanish horses with submucosal injection of Sulphuric Acid. A fibroendoscope and an He Ne laser were used to treat one of the ulcers and the second ulcer in each animal was left untreated, serving as control. Biopsy samples for the histological study were taken after the seventh laser therapy session from the two animal. Irradiated lesions cicatrised at 10.5 days and non irradiated lesions cicatrised at 18.0 days.
Statistical analysis revealed highly significant differences (P<0.0001) between the irradiated and control groups. Histological study of the control samples showed epithelial coagulation necrosis, edema, and microthrombi. However, in samples from the irradiated lesions no inflammatory edema, numerous active fibroblasts, connective tissue, and intensive epithelial regeneration were observed.
Macroscopic and microscopic results indicated that laser treatment accelerated the cicatrization. Irradiated lesions cicatrised faster than control. These results suggests beneficial effects of low level laser irradiation therapy on equine pharyngeal ulcerative lesions.